Methotrexate Drug Interactions



A
abacavir
abemaciclib
abiraterone
abrocitinib
acalabrutinib
acarbose
acetaminophen
acitretin
adagrasib
adalimumab
adefovir
adenovirus vaccine
ado-trastuzumab emtansine
afatinib
aldesleukin
alectinib
alefacept
alemtuzumab
allogeneic processed thymus tissue
alpelisib
ambrisentan
aminolevulinic acid
aminolevulinic acid topical
aminosalicylic acid
amiodarone
amoxicillin
amphotericin b
amphotericin b cholesteryl sulfate
amphotericin b lipid complex
amphotericin b liposomal
ampicillin
anakinra
anthrax vaccine adsorbed
apalutamide
asparaginase erwinia chrysanthemi
asparaginase escherichia coli
aspirin
atomoxetine
atorvastatin
atovaquone
avacopan
axitinib
azathioprine
azithromycin
B

bacampicillin
bacitracin
balsalazide
baricitinib
bcg
bcg vaccine
bedaquiline
belinostat
belumosudil
bempedoic acid
benazepril
bendamustine
bendroflumethiazide
benzthiazide
betamethasone
bexarotene
bicalutamide
bifidobacterium infantis
binimetinib
bismuth subsalicylate
black cohosh
bleomycin
blinatumomab
bortezomib
bosentan
bosutinib
botulism immune globulin
brentuximab
brewer's yeast
brigatinib
bromfenac
budesonide
bupropion
busulfan
C
cabazitaxel
caffeine
calaspargase pegol
canakinumab
candida albicans extract
cannabidiol
capmatinib
capreomycin
captopril
carbamazepine
carbenicillin
carboplatin
carfilzomib
carmustine
caspofungin
ceftazidime
celecoxib
ceritinib
cerivastatin
certolizumab
chaparral
charcoal
chenodeoxycholic acid
chikungunya vaccine, live (cvx 317)
chlorambucil
chloramphenicol
chloramphenicol ophthalmic
chloroquine
chlorothiazide
chlorthalidone
chlorzoxazone
cholera vaccine
cholera vaccine, live
choline salicylate
cidofovir
cinoxacin
ciprofloxacin
cisplatin
cladribine
clarithromycin
clavulanate
clofarabine
clotrimazole
cloxacillin
clozapine
cobimetinib
coccidioidin skin test
colistimethate
comfrey
corticorelin
corticotropin
cortisone
cosyntropin
crizotinib
cyclosporine
cytarabine
cytarabine liposomal
cytomegalovirus immune globulin
D

dacarbazine
daclizumab
danazol
danicopan
dantrolene
dapsone topical
darolutamide
darunavir
daunorubicin
daunorubicin liposomal
deferasirox
deferiprone
dehydroepiandrosterone
delafloxacin
delandistrogene moxeparvovec
demeclocycline
dengue vaccine
denosumab
deucravacitinib
dexamethasone
dexlansoprazole
diatrizoate
diclofenac
diclofenac topical
dicloxacillin
didanosine
diflunisal
digoxin
dimethyl fumarate
diroximel fumarate
disulfiram
divalproex sodium
docetaxel
doxorubicin
doxorubicin liposomal
doxycycline
dronedarone
duloxetine
duvelisib
E
efalizumab
efavirenz
efbemalenograstim alfa
eflapegrastim
eflornithine
elacestrant
elagolix
elotuzumab
elranatamab
eltrombopag
eluxadoline
emtricitabine
enalapril
enalaprilat
enasidenib
encorafenib
enoxacin
entecavir
entrectinib
epirubicin
eravacycline
erlotinib
erythromycin
esomeprazole
etanercept
ethambutol
ethanol
ethionamide
ethotoin
etidronate
etodolac
etoposide
etranacogene dezaparvovec
etrasimod
etretinate
everolimus
exenatide
F
febuxostat
fedratinib
felbamate
fenofibrate
fenofibric acid
fenoprofen
fexinidazole
fezolinetant
filgrastim
fingolimod
floxuridine
fluconazole
flucytosine
fludrocortisone
fluorouracil
fluoxymesterone
flurbiprofen
flutamide
fluvastatin
folic acid
fosinopril
fosphenytoin
fostamatinib
fostemsavir
fruquintinib
futibatinib
G

gadobenate dimeglumine
gallium citrate ga-67
ganciclovir
gatifloxacin
gefitinib
gemcitabine
gemfibrozil
gemifloxacin
gemtuzumab
gilteritinib
givosiran
glasdegib
golimumab
grepafloxacin
H
haemophilus b conjugate (hboc) vaccine
haemophilus b conjugate (prp-omp) vaccine
haemophilus b conjugate (prp-t) vaccine
haloperidol
hepatitis a adult vaccine
hepatitis a pediatric vaccine
hepatitis b adult vaccine
hepatitis b pediatric vaccine
histoplasmin
human papillomavirus vaccine
hydrochlorothiazide
hydrocortisone
hydroflumethiazide
hydroxychloroquine
hydroxyurea
I
ibandronate
ibritumomab
ibuprofen
idarubicin
idelalisib
ifosfamide
imatinib
immune globulin intravenous
immune globulin intravenous and subcutaneous
indapamide
indomethacin
infliximab
influenza virus vaccine, h1n1, inactivated
influenza virus vaccine, h1n1, live
influenza virus vaccine, h5n1
influenza virus vaccine, inactivated
influenza virus vaccine, live
inotersen
inotuzumab ozogamicin
interferon alfa-2a
interferon alfa-2b
interferon alfa-n1
interferon alfacon-1
interferon beta-1a
interferon beta-1b
interferon gamma-1b
iodamide
iodipamide
iodixanol
iohexol
iomeprol
iopamidol
iopromide
iothalamate
ioversol
ioxaglate
ioxilan
ipilimumab
isatuximab
isoniazid
isotretinoin
itraconazole
ivacaftor
ivosidenib
ixazomib
J
japanese enceph vacc sa14-14-2, inactivated
japanese encephalitis virus vaccine nakayama
K
kanamycin
kava
ketoconazole
ketoprofen
ketorolac
L
l-methylfolate
labetalol
lactobacillus acidophilus
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus rhamnosus gg
lamivudine
lamotrigine
lansoprazole
lapatinib
larotrectinib
lasmiditan
leflunomide
lenacapavir
lenalidomide
leniolisib
lenvatinib
leucovorin
levetiracetam
levofloxacin
levoketoconazole
levoleucovorin
levomefolate calcium
lisinopril
lomefloxacin
lomitapide
lomustine
loncastuximab tesirine
lovastatin
lurbinectedin
lutetium lu 177 dotatate
lyme disease vaccine
M

macitentan
magnesium salicylate
maraviroc
maribavir
measles virus vaccine
meclofenamate
mefenamic acid
meloxicam
melphalan
melphalan flufenamide
meningococcal conjugate vaccine
meningococcal group acwy conjugate-group b vaccine (cvx 316)
meningococcal group B vaccine
meningococcal polysaccharide vaccine
mephenytoin
mercaptopurine
mesalamine
metaxalone
methicillin
methimazole
methoxsalen
methoxyflurane
methyclothiazide
methyl aminolevulinate topical
methyldopa
methylprednisolone
methyltestosterone
metolazone
metrizamide
mezlocillin
midostaurin
milnacipran
minocycline
mipomersen
mirikizumab
mitomycin
mitotane
mitoxantrone
mixed respiratory vaccine
moexipril
momelotinib
monomethyl fumarate
moxifloxacin
multivitamin, prenatal
mumps skin test antigen
mumps virus vaccine
N
nabumetone
nadofaragene firadenovec
nafcillin
nalidixic acid
naltrexone
nandrolone
naproxen
natalizumab
naxitamab
nefazodone
neomycin
neratinib
nevirapine
niacin
niacinamide
nilotinib
nilutamide
nintedanib
niraparib
nirogacestat
nitazoxanide
nitisinone
nitrofurantoin
nitrous oxide
norfloxacin
O
ocrelizumab
ofloxacin
olaparib
olsalazine
olutasidenib
omacetaxine
omeprazole
onasemnogene abeparvovec
orlistat
oseltamivir
osimertinib
oteseconazole
oxacillin
oxaliplatin
oxandrolone
oxaprozin
oxymetholone
oxytetracycline
ozanimod
P
paclitaxel
paclitaxel protein-bound
pacritinib
palifermin
pamidronate
panobinostat
pantoprazole
paromomycin
pasireotide
pazopanib
pegaspargase
pegfilgrastim
peginterferon alfa-2a
peginterferon alfa-2b
peginterferon beta-1a
pemetrexed
pemoline
penicillin g benzathine
penicillin g potassium
penicillin g sodium
penicillin v potassium
pennyroyal
perindopril
pertussis, acellular
pexidartinib
phenazopyridine
phenylbutazone
phenytoin
pioglitazone
piperacillin
pirfenidone
piroxicam
pirtobrutinib
pitavastatin
plague vaccine
plazomicin
pneumococcal 13-valent vaccine
pneumococcal 15-valent conjugate vaccine
pneumococcal 20-valent conjugate vaccine
pneumococcal 23-polyvalent vaccine
pneumococcal 7-valent vaccine
polatuzumab vedotin
poliovirus vaccine, inactivated
poliovirus vaccine, live, trivalent
polymyxin b
polythiazide
ponatinib
ponesimod
porfimer
posaconazole
potassium acetate
potassium citrate
pralatrexate
pralsetinib
pravastatin
prednisolone
prednisone
pretomanid
probenecid
procaine penicillin
procarbazine
propylthiouracil
pyrazinamide
pyrimethamine
Q

quinapril
R
rabeprazole
rabies vaccine, human diploid cell
rabies vaccine, purified chick embryo cell
radium 223 dichloride
ramipril
red yeast rice
regorafenib
remdesivir
repotrectinib
resmetirom
respiratory syncytial virus immune globulin
rho (d) immune globulin
ribociclib
rifampin
rilonacept
rilpivirine
riluzole
ripretinib
ritlecitinib
ritonavir
rofecoxib
roflumilast
rolapitant
ropeginterferon alfa-2b
rosiglitazone
rosuvastatin
rotavirus vaccine
rsv vaccine pref3, recombinant
rsv vaccine, pref a-pref b, recombinant
rubella virus vaccine
rucaparib
ruxolitinib
S
saccharomyces boulardii lyo
safinamide
salsalate
samarium sm 153 lexidronam
sapropterin
sargramostim
sarilumab
sars-cov-2 (covid-19) ad26 vaccine, recombinant
sars-cov-2 (covid-19) chadox1 vaccine, recombinant
sars-cov-2 (covid-19) mrna (tozinameran 12y+) bivalent booster vaccine
sars-cov-2 (covid-19) mrna (tozinameran 5y-11y) bivalent booster vaccine
sars-cov-2 (covid-19) mrna (tozinameran 6m-4y) bivalent booster vaccine
sars-cov-2 (covid-19) mrna (tozinameran 6m-4y) bivalent vaccine
sars-cov-2 (covid-19) mrna-1273 (6m-5y bivalent booster) vaccine
sars-cov-2 (covid-19) mrna-1273 (bivalent booster) vaccine
sars-cov-2 (covid-19) mrna-1273 bivalent vaccine
sars-cov-2 (covid-19) mrna-1273 vaccine
sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 308)
sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 309)
sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 310)
sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 311)
sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 312)
sars-cov-2 (covid-19) mrna(tozinameran12y+) bivalent vaccine
sars-cov-2 (covid-19) nvx-cov2373 vaccine, recombinant
sars-cov-2 (covid-19) rs-nanoparticle vaccine, recombinant
sars-cov-2 (covid-19)mrna-1273(6y+ bivalent booster) vaccine
sars-cov-2 mrna (tozinameran 5y-11y) vaccine
sars-cov-2 mrna (tozinameran 6m-4y) vaccine
sars-cov-2 mrna (tozinameran-tris-sucrose) vaccine
sars-cov-2 mrna (tozinameran) vaccine
sars-cov-2 mrna-1273 (6m-5y) vaccine
sars-cov-2 mrna-1273 (6y-11y) vaccine
sars-cov-2 mrna-1273 (booster only) vaccine
sars-cov-2 nvx-cov2373 vaccine, recomb (cvx 313)
sars-cov-2 pres dtm (booster only) vaccine, recombinant
sars-cov-2(covid-19)mrna(tozinameran 5y-11y)bivalent vaccine
satralizumab
selpercatinib
selumetinib
simvastatin
siponimod
sipuleucel-T
sirolimus
skin test antigens, multiple
smallpox and monkeypox vaccine
smallpox vaccine
sodium acetate
sodium bicarbonate
sodium citrate
sodium lactate
sodium phosphate p32
sodium salicylate
sodium thiosalicylate
sorafenib
sotorasib
sparfloxacin
sparsentan
stanozolol
staphage lysate (spl)
stavudine
streptozocin
strontium-89 chloride
sulfadiazine
sulfadoxine
sulfamethizole
sulfamethoxazole
sulfasalazine
sulfisoxazole
sulindac
sunitinib
T

tacrine
tacrolimus
tafamidis
tafasitamab
talimogene laherparepvec
talquetamab
tamoxifen
tbo-filgrastim
teclistamab
tedizolid
telavancin
telbivudine
telithromycin
temozolomide
temsirolimus
tenofovir
tenofovir alafenamide
tepotinib
terbinafine
teriflunomide
testosterone
testosterone topical
tetanus toxoid
tetracycline
thalidomide
theophylline
thioguanine
thiotepa
ticarcillin
tick-borne encephalitis (inactivated) pediatric vaccine
tick-borne encephalitis (inactivated) vaccine
tipranavir
tivozanib
tizanidine
tocilizumab
tofacitinib
tolcapone
tolmetin
tolvaptan
topotecan
trabectedin
trandolapril
tretinoin
triamcinolone
trichlormethiazide
trichophyton skin test
trimethoprim
trimetrexate
trofinetide
troglitazone
troleandomycin
tromethamine
trovafloxacin
tuberculin purified protein derivative
tucatinib
typhoid vaccine, inactivated
typhoid vaccine, live
U
ublituximab
umbralisib
upadacitinib
ustekinumab
V
valacyclovir
valdecoxib
valganciclovir
valoctocogene roxaparvovec
valproic acid
vamorolone
vancomycin
varicella virus vaccine
vemurafenib
verteporfin
vinblastine
vincristine
vincristine liposome
vinorelbine
vitamin e
voclosporin
voriconazole
W
warfarin
Y
yellow fever vaccine
Z
zafirlukast
zalcitabine
zidovudine
zileuton
zoledronic acid
zoster vaccine live
zoster vaccine, recombinant


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